97久久久精品综合88久久-国语自产精品视频在线完整版-国产一区视频国产一区视频-亚洲欧美日韩国产精品一区二区

產(chǎn)品中心/ products

您的位置:首頁  -  產(chǎn)品中心  -    -  信號(hào)通路研究  -  7-乙基-10-羥基喜樹堿7-Ethyl-10-Hydroxycamptothecin(SN-38)

7-乙基-10-羥基喜樹堿7-Ethyl-10-Hydroxycamptothecin(SN-38)

  • 產(chǎn)品型號(hào):
  • 更新時(shí)間:2016-08-18

簡要描述:Product Name: 7-乙基-10-羥基喜樹堿7-Ethyl-10-Hydroxycamptothecin(SN-38)
CAS No.: 86639-52-3
Appearance: White to light yellow crystalline powder
Assay (On dried basis):>99%

產(chǎn)品詳情

Product Name: 7-Ethyl-10-Hydroxycamptothecin(SN-38); SN 38   7-乙基-10-羥基喜樹堿
CAS No.: 86639-52-3
Chemical Name: (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizi,2-b]quinoline-3,14(4H,12H)dione
Molecular formula: C22H20N2O5
Molecular weight: 392.40
Physical and chemical properties: 7-Ethyl-10-Hydroxycamptothecin is pale yellow to yellow crystalline powder, soluble in DSMO, methanol and ethanol. Not soluble in water and chloroform.
Strorage: Store in a cool and dry area, sealed and keep from direct light
Indication: It can be used in the treatment for non-small-cell lung cancer, rectum cancer and also can be used as the intermediates of Irinotecan

Appearance: White to light yellow crystalline powder
Assay (On dried basis):>99%    

Usage: Irinotecan Intermediate; A metabolite of Irinotecan, a DNA topoisomerase inhibitor.

Biological Activity: Active metabolite of CPT-11  that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 μM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 μM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).    

在線咨詢

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
產(chǎn)品中心
信號(hào)通路研究

CONTACT

辦公地址:中國(上海)自由貿(mào)易試驗(yàn)區(qū)臨港新片區(qū)新楊公路1666號(hào)3幢315室 EMAIL:2885066715@qq.com
掃碼關(guān)注公眾號(hào)
版權(quán)所有©2024 凱立德生物醫(yī)藥技術(shù)(上海)有限公司 All Rights Reserved   備案號(hào):滬ICP備15046197號(hào)-1   sitemap.xml技術(shù)支持:化工儀器網(wǎng)   管理登陸

TEL:021-58180488

掃碼關(guān)注公眾號(hào)
灵石县| 南昌市| 卓资县| 和政县| 莎车县| 墨脱县| 自贡市| 南乐县| 黑龙江省| 明星| 岑巩县| 固阳县| 香格里拉县| 广汉市| 万荣县| 迁安市| 开封县| 若羌县| 肥东县| 昭觉县| 深州市| 庆云县| 铜梁县| 正蓝旗| 鸡泽县| 定襄县| 利辛县| 宜宾市| 阜康市| 祁连县| 平罗县| 灵台县| 思南县| 曲水县| 会同县| 西丰县| 台中市| 蒲江县| 德安县| 历史| 栾川县|