97久久久精品综合88久久-国语自产精品视频在线完整版-国产一区视频国产一区视频-亚洲欧美日韩国产精品一区二区

產(chǎn)品中心/ products

您的位置:首頁  -  產(chǎn)品中心  -    -  信號(hào)通路研究  -  7-乙基-10-羥基喜樹堿7-Ethyl-10-Hydroxycamptothecin(SN-38)

7-乙基-10-羥基喜樹堿7-Ethyl-10-Hydroxycamptothecin(SN-38)

  • 產(chǎn)品型號(hào):
  • 更新時(shí)間:2016-08-18

簡要描述:Product Name: 7-乙基-10-羥基喜樹堿7-Ethyl-10-Hydroxycamptothecin(SN-38)
CAS No.: 86639-52-3
Appearance: White to light yellow crystalline powder
Assay (On dried basis):>99%

產(chǎn)品詳情

Product Name: 7-Ethyl-10-Hydroxycamptothecin(SN-38); SN 38   7-乙基-10-羥基喜樹堿
CAS No.: 86639-52-3
Chemical Name: (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizi,2-b]quinoline-3,14(4H,12H)dione
Molecular formula: C22H20N2O5
Molecular weight: 392.40
Physical and chemical properties: 7-Ethyl-10-Hydroxycamptothecin is pale yellow to yellow crystalline powder, soluble in DSMO, methanol and ethanol. Not soluble in water and chloroform.
Strorage: Store in a cool and dry area, sealed and keep from direct light
Indication: It can be used in the treatment for non-small-cell lung cancer, rectum cancer and also can be used as the intermediates of Irinotecan

Appearance: White to light yellow crystalline powder
Assay (On dried basis):>99%    

Usage: Irinotecan Intermediate; A metabolite of Irinotecan, a DNA topoisomerase inhibitor.

Biological Activity: Active metabolite of CPT-11  that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 μM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 μM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).    

在線咨詢

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫阿拉伯?dāng)?shù)字),如:三加四=7
產(chǎn)品中心
信號(hào)通路研究

CONTACT

辦公地址:中國(上海)自由貿(mào)易試驗(yàn)區(qū)臨港新片區(qū)新楊公路1666號(hào)3幢315室 EMAIL:2885066715@qq.com
掃碼關(guān)注公眾號(hào)
版權(quán)所有©2024 凱立德生物醫(yī)藥技術(shù)(上海)有限公司 All Rights Reserved   備案號(hào):滬ICP備15046197號(hào)-1   sitemap.xml技術(shù)支持:化工儀器網(wǎng)   管理登陸

TEL:021-58180488

掃碼關(guān)注公眾號(hào)
墨脱县| 江西省| 海南省| 滁州市| 五华县| 建水县| 崇左市| 上杭县| 大连市| 喀喇| 丹巴县| 渑池县| 太原市| 贺州市| 浠水县| 环江| 海盐县| 水富县| 伊宁市| 宝丰县| 庆云县| 琼结县| 广安市| 龙陵县| 昭觉县| 托克逊县| SHOW| 正镶白旗| 太仆寺旗| 壶关县| 潼关县| 淮阳县| 慈溪市| 承德县| 黎平县| 盖州市| 清镇市| 泰州市| 思南县| 阳城县| 彭泽县|