僅用于工業(yè)應(yīng)用或科學(xué)研究,不可用于人類或動(dòng)物的臨床診斷或治療,非藥用.Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus.Brefeldin A is also an autophagy and mitophagy inhibitor.Brefeldin A is a CRISPR/Cas9 activator.Brefeldin A inhibits HSV-1 and has anti-cancer activity.Brefeldin A (BFA) 是一種內(nèi)酯抗生素,是蛋白質(zhì)運(yùn)輸?shù)奶囟ㄒ种苿?。Brefeldin A 阻斷分泌蛋白和膜蛋白從內(nèi)質(zhì)網(wǎng)向高爾基體的轉(zhuǎn)運(yùn)。Brefeldin A 也是一種自噬 (autophagy) 和 mitophagy 抑制劑