僅用于工業(yè)應(yīng)用或科學(xué)研究,不可用于人類或動物的臨床診斷或治療,非藥用.Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities.Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells.Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma.Panobinostat 誘導(dǎo)細(xì)胞凋亡 (apoptosis) 和自噬 (autophagy)。Panobinostat 可用于難治性或復(fù)發(fā)性多發(fā)性骨髓瘤的研究