僅用于工業(yè)應(yīng)用或科學(xué)研究,不可用于人類(lèi)或動(dòng)物的臨床診斷或治療,非藥用. Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death